Sep 16, 2015

Alessia Quattrone i Bergen


Alessia Quattrone, MD som nylig ble medlem i CCI hadde en moderated poster på Joint Scandinavian Conference in Cardiothoracic Surgery i Bergen. Hun presenterte sin poster fredag 4. september.

Konferansen har nå blitt arrangert syv ganger og varte tre dager, fra torsdag 3. september til lørdag 5. september. Tilstede var internasjonalt anerkjente foredragsholdere spesialisert i LVAD/ECMO, hjerte- og lungekirurgi og GUCH.

Titelen på posterert var "Outcome of pregnancy in women with diagnosis of aortic coarctation".
Forfattere er; Alessia Quattrone, Anne Skeide, Katrine Onshus Eriksen, Harald Lindberg, Mette-Elise Estensen.

Posted by: Anonymous

P34 Outcome of pregnancy in women with diagnosis of aortic coarctation

Alessia Quattrone, Anne Skeide, Katrine Onshus Eriksen, Harald L. Lindberg, Mette-Elise Estensen.

Most female patients with coarctation of the aorta (CoA) reach childbearing age in a healthy condition which permits pregnancy. Aim: To report on maternal outcome of pregnancy in women with diagnosis of CoA. Methods: We reviewed our database for women with diagnosis of CoA and history of pregnancy. Cardiological data included were type and age at repair, hypertension (HT) before and/ or during pregnancy, residual/recurrent CoA. Obstetric data included number of pregnancies and preeclampsia.

27 patients with repaired CoA and 2 with native CoA had an overall of 48 pregnancies. 12 women (41%) had native/residual/recurrent CoA before and/or during pregnancy with hemodynamically significant gradient (HSG, >18 mmHg) in descending aorta (AoDesc); 2 of them were hypertensive. No association between HSG in AoDesc and HT during and/or before pregnancy was observed (p=0,82). 4 women had HT during pregnancy (13,7%). Three of them had their first repair after the age of 14. A late surgical repair (age> 14 years) is not associated with persistent HT after surgery (p=0,1). 2 patients (7%) developed preeclampsia, 1 had native CoA, both had HSG in AoDesc and were normotensive. Onset of preeclampsia isn’t related to HSG in AoDesc (p=0,64), and no relation between HT (during or before pregnancy) and preeclampsia has emerged (p= 0,57). The number of pregnancies does not affect the evolution of CoA, as there was no statistically significant difference in the values of AoDesc velocity among patients who had respectively 1, 2, 3 and 4 pregnancies (p=0,38).

Pregnancy is well tolerated in women with operated or native CoA, including those with native/ residual/ recurrent CoA. Rate of HT during pregnancy and preeclampsia were higher compared to the normal population; nevertheless no major adverse cardiovascular events (rupture of aortic aneurism, ischemic or hemorrhagic stroke, cardiovascular death) occurred.

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